By Stanley T. Crooke,Archie W. Prestayko
Part I is a normal evaluation of anti-cancer medicinal drugs as regards their motion mechanisms, pharmacokinetics, pharmacology, identified toxicities, and medical software. those medications contain alkylating brokers comparable to mitomycin C and nitrosoureas; plant alkaloids corresponding to maytansine; antibiotics similar to anthracyclines; platinum-containing complexes; antimetabolites; and hormones. half II examines the molecular pharmacology of a few significant drug periods, particularly, bleomycin and anthracycline. The textual content additionally discusses the chemistry, mechanism, and any structure-activity relationships present in those drug periods. half III discusses intimately the medical pharmacology of a few antitumor medicinal drugs, for instance, cisplatin and nitrosoureas. The textual content contains the scientific purposes, biochemistry, metabolism, and using mathematical versions in reading or describing ensuing facts.
The ebook is beneficial for pharmacologists, molecular biologists, and scientists taken with cancer-research.
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